Two dosing errors occur on page
1325 of Harrison's Principles of Internal Medicine, Volume
I, Edition 15.
The first error involves losartan in the Angiotensin Receptor
Blockers section. On the first and second lines of page 1325
is the statement "(e.g., losartan 50 mg qid)." The
correct dose of losartan should be 50 mg once daily.
The second error is mid-way down the first column on page
1325 in the B-adrenoceptor blockers section. In reference
to metoprolol CR/XL the statement "increasing over 4
weeks to a target dose of 200 mg qid" is incorrect. The
correct dose should state, "increasing over 4 weeks to
a target dose of 200 mg once daily." In both cases
the errata could lead to overdoses of these medications leading
to serious adverse events.
