Textbook and Publication Errata
Lexi-Comp notes an error in their
publications within the monograph for interferon gamma 1-beta.
Lexi-Comp has noted an error in their publications, including
the Drug Information Handbook, within the monograph for interferon
gamma 1-beta. This is related to differences between the units
used to express the dosage.
The current fields read:
Dosage: If severe reactions occur, modify dose (50% reduction)
or therapy should be discontinued until adverse reactions
abate.
Chronic granulomatous disease:
Children >1 year and Adults: S.C.: BSA 0.5 m2: 1.5 mcg/kg/dose
3 times/week
BSA >0.5 m2: 50 mcg/m2 (1.5 million int. units/m2) 3 times/week
Severe, malignant osteopetrosis:
Children >1 year: S.C.: BSA 0.5 m2: 1.5 mcg/kg/dose 3 times/week
BSA >0.5 m2: 50 mcg/m2 (1.5 million int. units/m2) 3 times/week
Dosage Forms: Injection: 100 mcg [3 million int. units] per
0.5 mL
This should be replaced by:
Dosage: If severe reactions occur, modify dose (50% reduction)
or therapy should be discontinued until adverse reactions
abate.
Chronic granulomatous disease:
Children >1 year and Adults: S.C.: BSA 0.5 m2: 1.5 mcg/kg/dose
3 times/week
BSA >0.5 m2: 50 mcg/m2 (1 million int. units/m2) 3 times/week
Severe, malignant osteopetrosis:
Children >1 year: S.C.: BSA 0.5 m2: 1.5 mcg/kg/dose 3 times/week
BSA >0.5 m2: 50 mcg/m2 (1 million int. units/m2) 3 times/week
Dosage Forms: Injection, solution: 100 mcg [2 million int.
units] (0.5 mL)
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