Mosby's Nursing Drug Reference
2005 contains inaccurate information regarding phenytoin administration.
On page 825 of Mosby's Nursing Drug Reference 2005, the following
directions for administration of phenytoin are provided:
"After diluting with diluent provided 2.2 ml/100 mg,
5.2 ml/250 mg, 1 ml/50 mg); shake; place vial in warm water
to dissolve powder; give through y-tube or 3 way stopck; inject
slowly <50 mg/min; clear IV tubing first with NS sol; use
inline filter; discard 4 hour after prparation. Inject into
large veins to prevent purple glove syndrome."
This is incorrect - phenytoin does not come as a powder for
dilution prior to IV administration. The publisher has been
notified.